- Patent Title: Stabilized nucleic acids encoding messenger ribonucleic acid (mRNA)
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Application No.: US16791076Application Date: 2020-02-14
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Publication No.: US11673911B2Publication Date: 2023-06-13
- Inventor: Christian Dombrowski
- Applicant: Intellia Therapeutics, Inc.
- Applicant Address: US MA Cambridge
- Assignee: Intellia Therapeutics, Inc.
- Current Assignee: Intellia Therapeutics, Inc.
- Current Assignee Address: US MA Cambridge
- Agency: McNeill Baur PLLC
- Main IPC: C12N15/11
- IPC: C12N15/11 ; C07H21/02 ; C12N15/63 ; C07K14/475 ; C07K14/52 ; C12N9/22
Abstract:
This disclosure relates to the field of poly-adenylated (poly-A) tails. In some embodiments, a DNA encodes a poly-A tail located 3′ to nucleotides encoding a protein of interest, wherein the poly-A tail comprises one or more non-adenine nucleotide.
Public/Granted literature
- US20200172564A1 Stabilized Nucleic Acids Encoding Messenger Ribonucleic Acid (mRNA) Public/Granted day:2020-06-04
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