An x-ray image orientation detection and correction system including a detection and correction computing device is provided. The processor of the computing device is programmed to execute a neural network model that is trained with training x-ray images as inputs and observed x-ray images as outputs. The observed x-ray images are the training x-ray images adjusted to have a reference orientation. The processor is further programmed to receive an unclassified x-ray image, analyze the unclassified x-ray image using the neural network model, and assign an orientation class to the unclassified x-ray image. If the assigned orientation class is not the reference orientation, the processor is programmed to adjust an orientation of the unclassified x-ray image using the neural network model, and output a corrected x-ray image. If the assigned orientation class is the reference orientation, the processor is programmed to output the unclassified x-ray image.