Described apparatuses and methods form adaptive cache lines having a configurable capacity from hardware cache lines having a fixed capacity. The adaptive cache lines can be formed in accordance with a programmable cache-line parameter. The programmable cache-line parameter can specify a capacity for the adaptive cache lines. The adaptive cache lines may be formed by combining respective groups of fixed-capacity hardware cache lines. The quantity of fixed-capacity hardware cache lines included in respective adaptive cache lines may be based on the programmable cache-line parameter. The programmable cache-line parameter can be selected in accordance with characteristics of the cache workload.