Invention Grant
- Patent Title: Chemical compounds as inhibitors of interleukin-1 activity
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Application No.: US17686183Application Date: 2022-03-03
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Publication No.: US11702428B2Publication Date: 2023-07-18
- Inventor: Jeffrey A. Stafford , James M. Veal , Lynnie Lin Trzoss , Christopher McBride
- Applicant: Genentech, Inc.
- Applicant Address: US CA South San Francisco
- Assignee: Genentech, Inc.
- Current Assignee: Genentech, Inc.
- Current Assignee Address: US CA South San Francisco
- Agent Katherine J. Mackenzie
- The original application number of the division: US17157749 2021.01.25
- Main IPC: C07D498/04
- IPC: C07D498/04 ; A61P37/02
Abstract:
The present disclosure relates to novel sulfonylurea and sulfonyl thiourea compounds and related compounds and their use in treating a disease or condition responsive to modulation of cytokines such as IL-1β and IL-18, modulation of NLRP3 or inhibition of the activation of NLRP3 or related components of the inflammatory process.
Public/Granted literature
- US20220306649A1 CHEMICAL COMPOUNDS AS INHIBITORS OF INTERLEUKIN-1 ACTIVITY Public/Granted day:2022-09-29
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