A configurable multi-function Peripheral Component Interchange Express (PCIe) endpoint controller, integrated in a system-on-chip (SoC), that exposes multiple functions of multiple processing subsystems (e.g., peripherals) to a host. The SoC may include a centralized transaction tunneling unit and a multi-function interrupt manager. The processing subsystems output data to the host via the centralized transaction tunneling unit, which translates addresses provided by the host to a local address of the SoC. Therefore, the centralized transaction tunneling unit enables those processing subsystems to consume addresses provided by the host without the need for software intervention and software-based translation. The SoC may also provide isolation between each function provided by the processing systems. The multi-function interrupt manager enables the endpoint controller to propagate interrupt messages received from the processing subsystems to the host.