- Patent Title: ROR1-positive mesenchymal stem cells and method for preparing same, pharmaceutical composition containing ROR1-positive mesenchymal stem cells and method for preparing same, and method for preventing or treating disease using ROR1-positive mesenchymal stem cells
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Application No.: US15755859Application Date: 2016-08-29
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Publication No.: US11707488B2Publication Date: 2023-07-25
- Inventor: Yoshifumi Ikeyama , Hiroyuki Nishida , Tomohiro Tsuda , Eiko Uno , Masayo Yumoto , Kazuma Suda , Mihoko Yoshino , Xuan Trung Ngo
- Applicant: ROHTO PHARMACEUTICAL CO., LTD.
- Applicant Address: JP Osaka
- Assignee: ROHTO PHARMACEUTICAL CO., LTD.
- Current Assignee: ROHTO PHARMACEUTICAL CO., LTD.
- Current Assignee Address: JP Osaka
- Agency: Osha Bergman Watanabe & Burton LLP
- International Application: PCT/JP2016/075251 2016.08.29
- International Announcement: WO2017/038784A 2017.03.09
- Date entered country: 2018-02-27
- Main IPC: A61K35/28
- IPC: A61K35/28 ; C12N5/0775
Abstract:
An object of the present invention is to provide novel mesenchymal stem cells demonstrating superior therapeutic effects against various diseases, a novel pharmaceutical composition containing these mesenchymal stem cells, and a method for preparing the same. The present invention relates to ROR1-positive mesenchymal stem cells. The ROR1-positive mesenchymal stem cells are preferably positive for CD29, CD73, CD90, CD105 and CD166 and are derived from umbilical cord or adipose tissue.
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