Invention Grant
- Patent Title: Heterodimeric antibodies that bind CD3 and CLDN6
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Application No.: US17690702Application Date: 2022-03-09
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Publication No.: US11739144B2Publication Date: 2023-08-29
- Inventor: Matthew S. Faber , Sung-Hyung Lee , Yoon Kyung Kim , Jing Qi , Kendra N. Avery , Seung Y. Chu , Alex Nisthal , Matthew J. Bernett , John R. Desjarlais , Chad Borchert
- Applicant: Xencor, Inc.
- Applicant Address: US CA Monrovia
- Assignee: Xencor, Inc.
- Current Assignee: Xencor, Inc.
- Current Assignee Address: US CA Pasadena
- Agency: Morgan, Lewis & Bockius, LLP
- Agent Louis-Vu T. Nguyen; Christopher J. Betti
- Main IPC: C07K16/28
- IPC: C07K16/28 ; A61P35/00 ; C07K16/46 ; C12N15/63
Abstract:
Provided herein are novel CLDN6 binding domains, and anti-CLDN6×anti-CD3 antibodies that include such CLDN6 binding domains. Also provided herein are methods of using such antibodies for the treatment of CLDN6-associated cancers.
Public/Granted literature
- US20220289839A1 HETERODIMERIC ANTIBODIES THAT BIND CD3 AND CLDN6 Public/Granted day:2022-09-15
Information query
