Invention Grant
- Patent Title: Surfaces having reduced non-specific binding and antigenicity
-
Application No.: US17015315Application Date: 2020-09-09
-
Publication No.: US11752213B2Publication Date: 2023-09-12
- Inventor: Angus Hucknall , Ashutosh Chilkoti , Daniel Joh , Nancy J. Ganson , Yizhi Qi , Michael S. Hershfield
- Applicant: Duke University
- Applicant Address: US NC Durham
- Assignee: Duke University
- Current Assignee: Duke University
- Current Assignee Address: US NC Durham
- Agency: Michael Best & Friedrich LLP
- Main IPC: A61K47/58
- IPC: A61K47/58 ; A61K47/59 ; C08L71/08 ; A61K47/64
Abstract:
Disclosed herein are compositions and methods for reducing the antigenicity of molecules. The antigenicity of a molecule may be reduced or eliminated by conjugating at least one branched polymer to the molecule to form a molecule-polymer conjugate. The branched polymer may include a backbone and a plurality of side chains, each side chain covalently attached to the backbone.
Public/Granted literature
- US20210046188A1 SURFACES HAVING REDUCED NON-SPECIFIC BINDING AND ANTIGENICITY Public/Granted day:2021-02-18
Information query
IPC分类:
