A method for intensification of advanced biological nitrogen removal and reduction of endocrine disrupting toxicity, and belongs to the technical field of advanced wastewater treatment includes the steps of utilizing the reaction of calcium sulfate and hydrogen peroxide solution under alkaline conditions to prepare nano-calcium peroxide (n-CP) oxygen-releasing materials, then the polyvinyl alcohol is used as a framework material, the sodium carboxymethyl cellulose is used as a bonding agent, the stearic acid is used as buffering agent and stabilizing agent, the prepared n-CP is used as an oxygen-releasing material, and the quartz sand is used to increase the material density to the sustained-release calcium peroxide nanoparticles (SR-nCPs) through the encapsulation method.