Technologies for accelerated HTTP message processing include a computing device having a network controller. The computing device may generate an HTTP message, frame the HTTP message to generate a transport protocol packet such as a TCP/IP packet or QUIC packet, and pass the transport protocol packet to the network controller. The network controller compresses the HTTP header of the HTTP message, encrypts the compressed HTTP message, and transmits the encrypted message to a remote device. The network controller may segment the transport protocol packet into multiple segmented packets. The network controller may receive transport protocol packets that include encrypted HTTP message. The network controller decrypts the encrypted HTTP message to generate a compressed HTTP message, decompresses the HTTP message, and steers the HTTP message to a receive queue based on contents of an HTTP header. The network controller may coalesce multiple transport protocol packets. Other embodiments are described and claimed.