- Patent Title: Sequencing nucleic acids via surface enhanced Raman spectroscopy
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Application No.: US16986108Application Date: 2020-08-05
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Publication No.: US11774366B2Publication Date: 2023-10-03
- Inventor: Gemma Mendonsa , Eric K. Wadleigh , Vivek Krishnamurthy , Riyan A. Mendonsa , Martin G. Blaber , Krishnan Subramanian
- Applicant: Seagate Technology LLC
- Applicant Address: US CA Fremont
- Assignee: SEAGATE TECHNOLOGY LLC
- Current Assignee: SEAGATE TECHNOLOGY LLC
- Current Assignee Address: US CA Fremont
- Agency: HOLZER PATEL DRENNAN
- Main IPC: C12Q1/6869
- IPC: C12Q1/6869 ; G01N21/65 ; C12N9/12 ; G01N27/447 ; B82Y30/00
Abstract:
A Surface-Enhanced Raman Spectroscopy (SERS) device to perform accurate label-free long-read DNA sequencing. A Raman sensor has a hot spot defined by plasmonic nanostructures and excited by at least one laser. An immobilized DNA polymerase can be used to pull a DNA template strand to be sequenced through the hot spot.
Public/Granted literature
- US20210148828A1 SEQUENCING NUCLEIC ACIDS VIA SURFACE ENHANCED RAMAN SPECTROSCOPY Public/Granted day:2021-05-20
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