- 专利标题: Modulating neural activity in brainstem circuitry with light
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申请号: US16767277申请日: 2018-11-30
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公开(公告)号: US11786750B2公开(公告)日: 2023-10-17
- 发明人: Michael W. Jenkins , Stephen J. Lewis , Hillel J. Chiel , Eric Duco Jansen , Junqi Zhuo , Emilie Lothet , Gjinovefa Kola
- 申请人: CASE WESTERN RESERVE UNIVERSITY , VANDERBILT UNIVERSITY
- 申请人地址: US OH Cleveland
- 专利权人: CASE WESTERN RESERVE UNIVERSITY,VANDERBILT UNIVERSITY
- 当前专利权人: CASE WESTERN RESERVE UNIVERSITY,VANDERBILT UNIVERSITY
- 当前专利权人地址: US OH Cleveland; US TN Nashville
- 代理机构: TAROLLI, SUNDHEIM, COVELL & TUMMINO, LLP
- 国际申请: PCT/US2018/063426 2018.11.30
- 国际公布: WO2019/109008A 2019.06.06
- 进入国家日期: 2020-05-27
- 主分类号: A61N5/06
- IPC分类号: A61N5/06 ; A61N5/067
摘要:
The present disclosure relates to modulating neural activity within brainstem circuitry to evoke a certain bodily function (e.g., cardiorespiratory response) in a patient. A controller can configure a light signal (such as an infrared light signal) to deliver an amount of radiant exposure to a specific portion of the brainstem for a time. The specific portion of the brainstem can include brainstem circuitry that is the control center for the certain bodily function. The configured light signal can be delivered to the specific portion of the brainstem by an optrode for the time. During application, the light signal can deliver the amount of radiant exposure to the specific portion of the brainstem to evoke the certain bodily function.
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