Disclosed are a protection equipment, system and method for the destruction of explosives. The protection equipment for the destruction of explosives includes four modules: an inner fence, an outer fence, an anti-leakage fence and a top cover. The modular equipment takes an overall nonmetal flexible composite structure, and the individual modules are light in weight and convenient to operate. It can be operated by two persons or a single person. A protective effect can be achieved during destruction of explosives by using the protection equipment, and even if the explosives explode during destruction, it will not cause injury to surrounding personnel. A protection system for explosive destruction based on the protection equipment can be used to destroy unexploded bomb or explosives under protective conditions, thereby achieving rapid emergency disposal without making contact with the explosives.