Invention Grant
- Patent Title: Solutions of quaternary and tertiary ammonium cation detergents to denature proteins, and kits for making them
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Application No.: US17398763Application Date: 2021-08-10
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Publication No.: US11858961B2Publication Date: 2024-01-02
- Inventor: Michael J. Kimzey , Francis T. Haxo , Vaishali Sharma
- Applicant: Agilent Technologies, Inc.
- Applicant Address: US CA Santa Clara
- Assignee: Agilent Technologies, Inc.
- Current Assignee: Agilent Technologies, Inc.
- Current Assignee Address: US CA Santa Clara
- Agency: Hyman IP Law
- Agent Laurence J. Hyman
- Main IPC: C07K1/00
- IPC: C07K1/00 ; C07K1/113 ; C11D1/62 ; C11D17/00
Abstract:
Ammonium cation detergents comprising a quaternary or tertiary ammonium cation can be used as detergents to denature proteins and are particularly useful in denaturing glycoproteins or glycopeptides prior to enzymatic deglycosylation. Ammonium cation detergents with sulfate or sulfonate anions are particularly useful.
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