- 专利标题: Self-assembling insect ferritin nanoparticles
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申请号: US17202231申请日: 2021-03-15
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公开(公告)号: US11939356B2公开(公告)日: 2024-03-26
- 发明人: Peter Kwong , Ivelin Georgiev , Michael Gordon Joyce , Masaru Kanekiyo , Aliaksandr Druz , Ulrich Baxa , Joseph Van Galen , Cheng Cheng , John Mascola , Yaroslav Tsybovsky , Yongping Yang , Barney Graham , Syed Mohammad Moin , Jeffrey Boyington
- 申请人: The United States of America, as represented by the Secretary, Department of Health and Human Services
- 申请人地址: US MD Bethesda
- 专利权人: The United States of America, as represented by the Secretary, Department of Health and Human Services
- 当前专利权人: The United States of America, as represented by the Secretary, Department of Health and Human Services
- 当前专利权人地址: US MD Bethesda
- 代理机构: Klarquist Sparkman, LLP
- 分案原申请号: US16312166
- 主分类号: C07K14/11
- IPC分类号: C07K14/11 ; A61K39/21 ; C07K14/08 ; C07K14/16 ; C07K14/165 ; C07K14/435 ; C12N7/00 ; A61K39/00
摘要:
Disclosed are recombinant insect ferritin nanoparticles that can be used to display two different trimeric antigens at an equal ratio. Also disclosed are nucleic acids encoding the recombinant insect ferritin nanoparticles and methods of producing the recombinant insect ferritin nanoparticles. Methods for eliciting an immune response in a subject are also provided.
公开/授权文献
- US20210198324A1 SELF-ASSEMBLING INSECT FERRITIN NANOPARTICLES 公开/授权日:2021-07-01
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