Methods and systems used in calibrating the position and/or orientation of a wearable device configured to be worn on a wrist or forearm of a user, the method comprises sensing a plurality of neuromuscular signals from the user using a plurality of sensors arranged on the wearable device, and providing the plurality of neuromuscular signals and/or signals derived from the plurality of neuromuscular signals as inputs to one or more trained autocalibration models, determining based, at least in part, on the output of the one or more trained autocalibration models, a current position and/or orientation of the wearable device on the user, and generating a control signal based, at least in part, on the current position and/or orientation of the wearable device on the user and the plurality of neuromuscular signals.