Invention Grant
- Patent Title: Nuclear transport modulators and uses thereof
-
Application No.: US17409150Application Date: 2021-08-23
-
Publication No.: US11945794B2Publication Date: 2024-04-02
- Inventor: Erkan Baloglu , Sharon Shacham , Dilara McCauley , Trinayan Kashyap , William Senapedis , Yosef Landesman , Gali Golan , Ori Kalid , Sharon Shechter
- Applicant: Karyopharm Therapeutics Inc.
- Applicant Address: US MA Newton
- Assignee: Karyopharm Therapeutics Inc.
- Current Assignee: Karyopharm Therapeutics Inc.
- Current Assignee Address: US MA Newton
- Agency: FOLEY HOAG LLP
- Main IPC: C07D249/08
- IPC: C07D249/08 ; A61K31/4196 ; A61K31/422 ; A61K31/426 ; A61K31/4439 ; A61K31/4709 ; A61K31/501 ; A61K31/506 ; A61P3/04 ; A61P11/00 ; A61P17/02 ; A61P25/00 ; A61P25/28 ; A61P27/02 ; A61P29/00 ; A61P31/12 ; A61P35/00 ; A61P37/00 ; C07D401/06 ; C07D403/06 ; C07D405/06 ; C07D413/06 ; C07D417/06
Abstract:
The present invention relates to compounds of formula I:
and pharmaceutically acceptable salts thereof, pharmaceutical compositions comprising the compounds of formula I or their pharmaceutically acceptable salts, and methods of using said compounds, salts and compositions in the treatment of various disorders associated with CRM1 activity.
and pharmaceutically acceptable salts thereof, pharmaceutical compositions comprising the compounds of formula I or their pharmaceutically acceptable salts, and methods of using said compounds, salts and compositions in the treatment of various disorders associated with CRM1 activity.
Public/Granted literature
- US20220177445A1 NUCLEAR TRANSPORT MODULATORS AND USES THEREOF Public/Granted day:2022-06-09
Information query
