- 专利标题： Quantitation of insulin-like growth factor-I and insulin-like growth factor-II with high-resolution mass spectrometry
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申请号： US17949863申请日： 2022-09-21
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公开(公告)号： US11953507B2公开(公告)日： 2024-04-09
- 发明人: Cory Bystrom , Shijun Sheng , Nigel Clarke , Richard Reitz
- 申请人： Quest Diagnostics Investments Incorporated
- 申请人地址： US DE Wilmington
- 专利权人： Quest Diagnostics Investments Incorporated
- 当前专利权人： Quest Diagnostics Investments Incorporated
- 当前专利权人地址： US DE Wilmington
- 代理机构： Foley & Lardner LLP
- 主分类号： G01N33/74
- IPC分类号： G01N33/74 ; G01N33/68
摘要：
Methods are provided for determining the amount of an IGF-I and/or IGF-II protein in a sample using high resolution/high accuracy mass spectrometry. The methods generally comprise enriching an IGF-I and/or IGF-II protein in a sample, ionizing an IGF-I and/or IGF-II protein from the sample to generate IGF-I and/or IGF-II protein ions, and determining the amount of IGF-I and/or IGF-II protein ions with high resolution/high accuracy mass spectrometry.
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