A tool holder for firmly holding a wide range of sizes and shapes of tool handles includes a holder handle, a cage assembly, a clamp, a locking coupling, and a threaded actuator. The cage assembly includes a pair of axially spaced apart supports having axially aligned through openings sized for receiving tool handles of different sizes and shapes. The clamp is transversely movable between the supports in opposite directions for releasably clamping the tool handle against the supports. The locking coupling is interposed between the holder handle and the cage assembly for selectively adjusting the angular orientation of the cage assembly relative to the holder handle. The threaded actuator is operable to lock or unlock the locking coupling for permitting or restricting adjustment of the angular orientation of the cage assembly relative to the holder handle.