![Processes for the preparation of (3S,4R)-3-ethyl-4-(3H-imidazo[1,2-a]pyrrolo[2,3-e]-pyrazin-8-yl)-n-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide and solid state forms thereof](/docs/US/2024-05-28/US11993605B2/abs.jpg.600x600.jpg)
- 专利标题： Processes for the preparation of (3S,4R)-3-ethyl-4-(3H-imidazo[1,2-a]pyrrolo[2,3-e]-pyrazin-8-yl)-n-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide and solid state forms thereof
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申请号： US18176664申请日： 2023-03-01
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公开(公告)号： US11993605B2公开(公告)日： 2024-05-28
- 发明人: Mohamed-Eslam F. Mohamed , Ahmed A. Othman , Ben Klünder , Aileen L. Pangan , Jaclyn Kay Anderson , Jeffrey W. Voss , Robert J. Padley , Heidi S. Camp
- 申请人： AbbVie Inc.
- 申请人地址： US IL North Chicago
- 专利权人： AbbVie Inc.
- 当前专利权人： AbbVie Inc.
- 当前专利权人地址： US IL North Chicago
- 代理机构： WOMBLE BOND DICKINSON (US) LLP
- 代理商 Danielle L. Herritt; Scott R. Breining
- 主分类号： A61K31/4985
- IPC分类号： A61K31/4985 ; A61K9/00 ; A61K47/12 ; A61K47/38 ; C07D487/14
![Processes for the preparation of (3S,4R)-3-ethyl-4-(3H-imidazo[1,2-a]pyrrolo[2,3-e]-pyrazin-8-yl)-n-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide and solid state forms thereof](/abs-image/US/2024/05/28/US11993605B2/abs.jpg.150x150.jpg)
摘要：
The present disclosure relates to processes for preparing (3S,4R)-3-ethyl-4-3H-imidazo[1,2-a]pyrrolo[2,3-e]pyrazin-8-yl)-N-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide, solid state forms thereof, and corresponding pharmaceutical compositions, methods of treatment (including treatment of rheumatoid arthritis, ankylosing spondylitis, and psoriatic arthritis), kits, methods of synthesis, and products-by-process.
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