A second problem Hamiltonian may replace a first problem Hamiltonian during evolution of an analog processor (e.g., quantum processor) during a first iteration in solving a first problem. This may be repeated during a second, or further successive iterations on the first problem, following re-initialization of the analog processor. An analog processor may evolve under a first non-monotonic evolution schedule during a first iteration, and second non-monotonic evolution schedule under second, or additional non-monotonic evolution schedule under even further iterations. A first graph and second graph may each be processed to extract final states versus a plurality of evolution schedules, and a determination made as to whether the first graph is isomorphic with respect to the second graph. An analog processor may evolve by decreasing a temperature of, and a set of quantum fluctuations, within the analog processor until the analog processor reaches a state preferred by a problem Hamiltonian.