The present disclosure is related to hybrid desalination systems and associated methods. The hybrid desalination system can comprise a first desalination unit comprising a reverse osmosis unit and a second desalination unit fluidically connected to the first desalination unit, wherein the second desalination unit comprises a humidification-dehumidification desalination apparatus. The present disclosure is also related to systems and methods for the formation of solid salts using a humidifier. According to certain embodiments, the flow velocity of a gas in the humidifier can be relatively high during the formation of the solid salt. In some embodiments, the humidifier comprises a multi-stage bubble column humidifier.