Invention Grant
- Patent Title: Methods for labeling DNA fragments to reconstruct physical linkage and phase
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Application No.: US17373736Application Date: 2021-07-12
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Publication No.: US12043828B2Publication Date: 2024-07-23
- Inventor: Daniel Rokhsar , Richard E. Green, Jr.
- Applicant: The Regents of the University of California
- Applicant Address: US CA Oakland
- Assignee: The Regents of the University of California
- Current Assignee: The Regents of the University of California
- Current Assignee Address: US CA Oakland
- Agency: Gavrilovich, Dodd & Lindsey LLP
- Main IPC: C12N15/10
- IPC: C12N15/10 ; C12Q1/6844 ; C12Q1/6855 ; C12Q1/6883
Abstract:
The disclosure provides for methods to form compact cross-linked polynucleotide/protein structures that can then be labeled using a barcoded oligonucleotide array in order to reconstruct physical linkage and/or genomic proximity (and phase) of polynucleotide fragments.
Public/Granted literature
- US20220112487A1 METHODS FOR LABELING DNA FRAGMENTS TO RECONSTRUCT PHYSICAL LINKAGE AND PHASE Public/Granted day:2022-04-14
Information query
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