公开(公告)号：US11091758B2

公开(公告)日：2021-08-17

申请号：US15103821

申请日：2014-12-11

Applicant: The Regents of the University of California

Inventor： Daniel Rokhsar ,  Richard E. Green, Jr.

IPC: C12N15/10 ,  C12Q1/6844 ,  C12Q1/6855 ,  C12Q1/6883

Abstract: The disclosure provides for methods to form compact cross-linked polynucleotide/protein structures that can then be labeled using a barcoded oligonucleotide array in order to reconstruct physical linkage and/or genomic proximity (and phase) of polynucleotide fragments.

公开(公告)号：US11081209B2

公开(公告)日：2021-08-03

申请号：US16128297

申请日：2018-09-11

Applicant: The Regents of the University of California

Inventor： Richard E. Green, Jr. ,  Liana F. Lareau

IPC: C12Q1/68 ,  G16B30/00 ,  G16B35/00 ,  G16C20/60 ,  C12Q1/6869

Abstract: The disclosure provides methods to assemble genomes of eukaryotic or prokaryotic organisms. The disclosure further provides methods for haplotype phasing and meta-genomics assemblies.

公开(公告)号：US12043828B2

公开(公告)日：2024-07-23

申请号：US17373736

申请日：2021-07-12

Applicant: The Regents of the University of California

Inventor： Daniel Rokhsar ,  Richard E. Green, Jr.

IPC: C12N15/10 ,  C12Q1/6844 ,  C12Q1/6855 ,  C12Q1/6883

CPC classification number: C12N15/1065 ,  C12Q1/6844 ,  C12Q1/6855 ,  C12Q1/6883 ,  C12Q2600/156 ,  C12Q1/6844 ,  C12Q2523/101 ,  C12Q2525/155 ,  C12Q2531/119 ,  C12Q2563/179 ,  C12Q2565/501 ,  C12Q1/6855 ,  C12Q2521/313 ,  C12Q2523/101 ,  C12Q2563/179

Abstract: The disclosure provides for methods to form compact cross-linked polynucleotide/protein structures that can then be labeled using a barcoded oligonucleotide array in order to reconstruct physical linkage and/or genomic proximity (and phase) of polynucleotide fragments.

公开(公告)号：US11935626B2

公开(公告)日：2024-03-19

申请号：US17066868

申请日：2020-10-09

Applicant: The Regents of the University of California

Inventor： Richard E. Green, Jr. ,  Liana F. Lareau

IPC: C12Q1/6874 ,  G16B30/00 ,  G16B30/20

CPC classification number: G16B30/20 ,  C12Q1/6874 ,  G16B30/00

Abstract: The disclosure provides methods to assemble genomes of eukaryotic or prokaryotic organisms. The disclosure further provides methods for haplotype phasing and meta-genomics assemblies.

公开(公告)号：US10825553B2

公开(公告)日：2020-11-03

申请号：US15900723

申请日：2018-02-20

Applicant: The Regents of the University of California

Inventor： Richard E. Green, Jr. ,  Liana F. Lareau

IPC: C12Q1/68 ,  G16B30/00 ,  C12Q1/6874

Abstract: The disclosure provides methods to assemble genomes of eukaryotic or prokaryotic organisms. The disclosure further provides methods for haplotype phasing and meta-genomics assemblies.

公开(公告)号：US10529443B2

公开(公告)日：2020-01-07

申请号：US16202042

申请日：2018-11-27

Applicant: The Regents of the University of California

Inventor： Richard E. Green, Jr. ,  Liana F. Lareau

IPC: C12Q1/68 ,  G16B30/00 ,  C12Q1/6874

Abstract: The disclosure provides methods to assemble genomes of eukaryotic or prokaryotic organisms. The disclosure further provides methods for haplotype phasing and meta-genomics assemblies.

公开(公告)号：US10089437B2

公开(公告)日：2018-10-02

申请号：US14764945

申请日：2014-01-31

Applicant: The Regents of the University of California

Inventor： Richard E. Green, Jr. ,  Liana F. Lareau

IPC: C12Q1/68 ,  G06F19/22 ,  C12Q1/6869 ,  C40B30/02

Abstract: The disclosure provides methods to assemble genomes of eukaryotic or prokaryotic organisms. The disclosure further provides methods for haplotype phasing and meta-genomics assemblies.

公开(公告)号：US09910955B2

公开(公告)日：2018-03-06

申请号：US15167880

申请日：2016-05-27

Applicant: The Regents of the University of California

Inventor： Richard E. Green, Jr. ,  Liana F. Lareau

IPC: G06F19/22 ,  C12Q1/68

CPC classification number: G06F19/22 ,  C12Q1/6874

Abstract: The disclosure provides methods to assemble genomes of eukaryotic or prokaryotic organisms. The disclosure further provides methods for haplotype phasing and meta-genomics assemblies.

公开(公告)号：US09411930B2

公开(公告)日：2016-08-09

申请号：US14170339

申请日：2014-01-31

Applicant: The Regents of the University of California

Inventor： Richard E. Green, Jr. ,  Liana F. Lareau

IPC: C12Q1/68 ,  G06F19/22

CPC classification number: G06F19/22 ,  C12Q1/6874

Abstract: The disclosure provides methods to assemble genomes of eukaryotic or prokaryotic organisms. The disclosure further provides methods for haplotype phasing and meta-genomics assemblies.

Abstract translation: 本公开提供了组装真核生物或原核生物的基因组的方法。 本公开进一步提供了用于单倍型定相和元基因组装配的方法。