- 专利标题： Anti-alpha-synuclein antibodies and uses thereof
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申请号： US16475853申请日： 2018-01-05
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公开(公告)号： US12049493B2公开(公告)日： 2024-07-30
- 发明人: Jinhyung Ahn , Sungwon An , Dongin Kim , Eunsil Sung , Jaehyun Eom , Sang Hoon Lee , Seung-Jae Lee , Tae Kyung Kim , Min Sun Choi , Weonkyoo You , Jaeho Jung , Juhee Kim , Jinwon Jung , Yeunju Kim , Yonggyu Son , Byungje Sung
- 申请人： ABL Bio Inc.
- 申请人地址： KR Seongnam-si
- 专利权人： ABL BIO INC.
- 当前专利权人： ABL BIO INC.
- 当前专利权人地址： KR Seongnam-si
- 代理机构： Steptoe LLP
- 代理商 Z. Ying Li; Wyan-Ching M. Lee
- 优先权： KR 20180001641 2018.01.05
- 国际申请： PCT/KR2018/000239 2018.01.05
- 国际公布： WO2018/128454A 2018.07.12
- 进入国家日期： 2019-07-03
- 主分类号： C07K16/18
- IPC分类号： C07K16/18 ; A61K39/00 ; A61P25/14 ; G01N33/68
摘要：
The disclosure discloses anti α-Syn antibodies preferentially recognizing α-Syn aggregates. The antibodies of the present invention bind to α-Syn aggregates with high affinity and specificity and inhibit accumulation or intercellular transfer of α-Syn aggregates, and thus can be used for detection, diagnosis and/or treatment or prevention of various diseases caused by the accumulation of α-Syn aggregates.
公开/授权文献
- US20230227540A1 ANTI-Alpha-SYN ANTIBODY AND USE THEREOF 公开/授权日：2023-07-20
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