Invention Grant
- Patent Title: Hepatitis B antiviral agents
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Application No.: US17143326Application Date: 2021-01-07
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Publication No.: US12054493B2Publication Date: 2024-08-06
- Inventor: Yao-Ling Qiu , Xuri Gao , Wei Li , Hui Cao , Meizhong Jin , Jorden Kass , Xiaowen Peng , Yat Sun Or
- Applicant: ENANTA PHARMACEUTICALS, INC.
- Applicant Address: US MA Watertown
- Assignee: Enanta Pharmaceuticals, Inc.
- Current Assignee: Enanta Pharmaceuticals, Inc.
- Current Assignee Address: US MA Watertown
- Agency: Elmore Patent Law Group, P.C.
- Agent Edgar W. Harlan; Carolyn S. Elmore
- The original application number of the division: US15450125 2017.03.06
- Main IPC: C07D493/08
- IPC: C07D493/08 ; A61K31/167 ; A61K31/18 ; A61K31/196 ; A61K31/215 ; A61K31/223 ; A61K31/277 ; A61K31/325 ; A61K31/335 ; A61K31/336 ; A61K31/341 ; A61K31/351 ; A61K31/357 ; A61K31/365 ; A61K31/39 ; A61K31/401 ; A61K31/41 ; A61K31/415 ; A61K31/416 ; A61K31/4164 ; A61K31/421 ; A61K31/426 ; A61K31/439 ; A61K31/44 ; A61K31/4402 ; A61K31/4409 ; A61K31/4425 ; A61K31/445 ; A61K31/4545 ; A61K31/5377 ; A61K31/655 ; C07B59/00 ; C07C235/56 ; C07C311/53 ; C07C317/32 ; C07C317/44 ; C07C323/42 ; C07C323/62 ; C07D207/16 ; C07D211/54 ; C07D213/52 ; C07D213/81 ; C07D213/89 ; C07D231/12 ; C07D233/64 ; C07D257/04 ; C07D261/02 ; C07D261/08 ; C07D261/20 ; C07D263/52 ; C07D277/26 ; C07D295/088 ; C07D303/26 ; C07D303/34 ; C07D307/32 ; C07D307/33 ; C07D309/08 ; C07D313/04 ; C07D317/72 ; C07D327/10 ; C07D401/04 ; C07D451/04 ; C07D493/04
Abstract:
The present invention discloses compounds of Formula (I), or pharmaceutically acceptable salts, esters, or prodrugs thereof:
X-A-Y-L-R (I)
which inhibit the protein(s) encoded by hepatitis B virus (HBV) or interfere with the function of the HBV life cycle of the hepatitis B virus and are also useful as antiviral agents. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject suffering from HBV infection. The invention also relates to methods of treating an HBV infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention.
X-A-Y-L-R (I)
which inhibit the protein(s) encoded by hepatitis B virus (HBV) or interfere with the function of the HBV life cycle of the hepatitis B virus and are also useful as antiviral agents. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject suffering from HBV infection. The invention also relates to methods of treating an HBV infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention.
Public/Granted literature
- US20210230176A1 HEPATITIS B ANTIVIRAL AGENTS Public/Granted day:2021-07-29
Information query
