发明授权
- 专利标题： Gene expression profiles associated with sub-clinical kidney transplant rejection
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申请号： US16569119申请日： 2019-09-12
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公开(公告)号： US12060611B2公开(公告)日： 2024-08-13
- 发明人: Daniel Salomon , John Friedewald , Sunil Kurian , Michael M. Abecassis , Steve Head , Phillip Ordoukhanian
- 申请人： THE SCRIPPS RESEARCH INSTITUTE , NORTHWESTERN UNIVERSITY
- 申请人地址： US CA La Jolla
- 专利权人： THE SCRIPPS RESEARCH INSTITUTE,NORTHWESTERN UNIVERSITY
- 当前专利权人： THE SCRIPPS RESEARCH INSTITUTE,NORTHWESTERN UNIVERSITY
- 当前专利权人地址： US CA La Jolla; US IL Evanston
- 代理机构： Duane Morris LLP
- 代理商 Thomas J. Kowalski
- 主分类号： C12Q1/68
- IPC分类号： C12Q1/68 ; C12Q1/6883 ; G16B20/00 ; G16B40/20 ; G16B40/30 ; G16H20/40 ; G16H50/20 ; G16H50/30 ; G16B25/10
摘要：
By a genome-wide gene analysis of expression profiles of over 50,000 known or putative gene sequences in peripheral blood, the present inventors have identified a consensus set of gene expression-based molecular biomarkers associated with subclinical acute rejection (subAR). These genes sets are useful for diagnosis, prognosis, monitoring of subAR.
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