This application relates to a method of manufacturing a knife using a multilayer material. In one aspect, the method includes preparing a multilayer material for manufacturing a knife, and heating and then forging the multilayer material to form a knife-shaped structure including a blade part and a handle part. The method also includes grinding the blade part to form a sharpened knife-edge and applying mud, including kaolin and white clay, to an entire surface of the knife-shaped structure and removing the mud applied to the blade part. The method further includes heating the knife-shaped structure applied with the mud, and quenching the heated knife-shaped structure through oil-cooling. The method further includes etching a surface of the quenched knife-shaped structure to form a pattern on the surface and grinding the surface-etched knife-shaped structure to form a knife having a final shape.