- 专利标题: Immunogenic sequences from a phage tail length tape measure protein, bacteria expressing the same and their use in treating a cancer
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申请号: US16959042申请日: 2018-12-21
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公开(公告)号: US12102672B2公开(公告)日: 2024-10-01
- 发明人: Laurence Zitvogel
- 申请人: INSTITUT GUSTAVE ROUSSY , INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE , UNIVERSITE PARIS-SACLAY , CENTRE HOSPITALIER UNIVERSITAIRE DE RENNES , UNIVERSITE DE RENNES
- 申请人地址: FR Villejuif
- 专利权人: INSTITUT GUSTAVE ROUSSY,INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE,UNIVERSITE PARIS-SACLAY,CENTRE HOSPITALIER UNIVERSITAIRE DE RENNES,UNIVERSITE DE RENNES
- 当前专利权人: INSTITUT GUSTAVE ROUSSY,INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE,UNIVERSITE PARIS-SACLAY,CENTRE HOSPITALIER UNIVERSITAIRE DE RENNES,UNIVERSITE DE RENNES
- 当前专利权人地址: FR Villejuif; FR Paris; FR Gif Sur Yvette; FR Rennes; FR Rennes
- 代理机构: Arrigo, Lee, Guttman & Mouta-Bellum LLP
- 优先权: EP 306980 2017.12.29
- 国际申请: PCT/EP2018/086812 2018.12.21
- 国际公布: WO2019/129753A 2019.07.04
- 进入国家日期: 2020-06-29
- 主分类号: A61K39/12
- IPC分类号: A61K39/12 ; A61K35/76 ; A61K45/00 ; A61P35/00 ; C07K14/005 ; C07K14/74 ; C12N5/0783 ; C12N15/74 ; C12Q1/02 ; C12Q1/6886 ; G01N33/50 ; G01N33/543 ; A61K39/00
摘要:
The present invention relates to the field of probiotic adjuvantization of anticancer treatments. In particular, the present invention concerns immunogenic sequences from a prophage present in bacteria identified as efficient adjuvants of cancer treatments. The invention provides bacterial compositions expressing immunogenic sequences from this prophage, immunogenic compositions comprising such sequences and methods using sequences from this prophage, for increasing the anticancer armamentarium.
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