公开(公告)号：US12102672B2

公开(公告)日：2024-10-01

申请号：US16959042

申请日：2018-12-21

申请人： INSTITUT GUSTAVE ROUSSY ,  INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE ,  UNIVERSITE PARIS-SACLAY ,  CENTRE HOSPITALIER UNIVERSITAIRE DE RENNES ,  UNIVERSITE DE RENNES

发明人： Laurence Zitvogel

IPC分类号： A61K39/12 ,  A61K35/76 ,  A61K45/00 ,  A61P35/00 ,  C07K14/005 ,  C07K14/74 ,  C12N5/0783 ,  C12N15/74 ,  C12Q1/02 ,  C12Q1/6886 ,  G01N33/50 ,  G01N33/543 ,  A61K39/00

CPC分类号： A61K39/12 ,  A61K35/76 ,  A61K45/00 ,  A61P35/00 ,  C07K14/005 ,  C07K14/70539 ,  C12N5/0636 ,  C12N15/746 ,  C12Q1/025 ,  C12Q1/6886 ,  G01N33/5091 ,  G01N33/54306 ,  A61K2039/5154 ,  A61K2039/523 ,  C12N2509/00 ,  C12N2795/10321 ,  C12N2795/10333 ,  C12N2795/10343 ,  C12Q2600/106 ,  C12Q2600/158 ,  G01N2800/52

摘要： The present invention relates to the field of probiotic adjuvantization of anticancer treatments. In particular, the present invention concerns immunogenic sequences from a prophage present in bacteria identified as efficient adjuvants of cancer treatments. The invention provides bacterial compositions expressing immunogenic sequences from this prophage, immunogenic compositions comprising such sequences and methods using sequences from this prophage, for increasing the anticancer armamentarium.

公开(公告)号：US20240170852A1

公开(公告)日：2024-05-23

申请号：US18510489

申请日：2023-11-15

申请人： THALES ,  UNIVERSITE DE RENNES ,  CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE ,  INSA DE RENNES ,  NANTES UNIVERSITE ,  CENTRALESUPELEC

发明人： Hervé LEGAY ,  Charalampos STOUMPOS ,  Jean-Philippe FRAYSSE

IPC分类号： H01Q13/08 ,  H04B7/06

CPC分类号： H01Q13/085 ,  H04B7/0639

摘要： A device for controlling radiofrequency beams comprising a set of cells. Each cell comprises a support frame and an excitation element, and emits and/or receives beams in an invariant manner according to the direction of propagation of the beam. The frame is inscribed within a generally tubular shape, oriented along the axis Z of a reference frame, having a cross section of perimeter P, and comprises an entrance, an exit and a number N of slots between the exit and a position Zo located between the entrance and the exit. Each slot has a variable width along Z. The slot width has a minimum value at the position Zo, and a maximum value at the exit that is determined on the basis of the perimeter P and the number N.

公开(公告)号：US20240116923A1

公开(公告)日：2024-04-11

申请号：US18273878

申请日：2022-01-25

申请人： Seabelife ,  Centre National de la Recherche Scientifique (CNRS) ,  Sorbonne Universite ,  INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE (INSERM) ,  Université Claude Bernard Lyon 1 ,  Universite de Rennes 1

发明人： Stéphane BACH ,  Arnaud COMTE ,  Claire DELEHOUZE ,  Marie-Thérèse DIMANCHE-BOITREL ,  Peter GOEKJIAN

IPC分类号： C07D471/04 ,  A61K31/404 ,  A61K31/437 ,  A61K31/444 ,  A61K31/4545 ,  A61K31/496 ,  A61K31/5377 ,  A61P39/06 ,  C07D209/12

CPC分类号： C07D471/04 ,  A61K31/404 ,  A61K31/437 ,  A61K31/444 ,  A61K31/4545 ,  A61K31/496 ,  A61K31/5377 ,  A61P39/06 ,  C07D209/12

摘要： The present invention relates to a compound of the following general formula (I) or a pharmaceutically acceptable salt and/or solvate thereof, for use as drug for inhibiting ferroptosis.

公开(公告)号：US20240116876A1

公开(公告)日：2024-04-11

申请号：US17925738

申请日：2021-05-19

申请人： Institut National de la Santé et de la Recherche Médicale (INSERM) ,  Universite de Bretagne Occidentale ,  Ecole Nationale Superieure de Chimie de Rennes ,  Institut National des Sciences Appliquees de Rennes ,  Universite Nangui Abrogoua ,  Centre National de la Recherche Scientifique ,  Universite de Rennes 1

发明人： Jean Pierre Bazureau ,  Déliko Camille Dago ,  Lou Anna Voli ,  Olivier Mignen ,  Christophe Brigaudeau ,  Yves-Alain Berko

IPC分类号： C07D235/04 ,  A61P35/00

CPC分类号： C07D235/04 ,  A61P35/00

摘要： The present invention provides SOCE inhibitors that are useful as therapeutic agents in a variety of applications. The present invention also relates to pharmaceutical compositions, products and kits comprising such SOCE inhibitors, and methods of using the SOCE inhibitors in the treatment of a variety of diseases.

公开(公告)号：US20240018674A1

公开(公告)日：2024-01-18

申请号：US18038529

申请日：2021-11-29

申请人： CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE ,  ECOLE NATIONALE SUPERIEURE DE CHIMIE DE RENNES ,  UNIVERSITE D'AIXMARSEILLE ,  UNIVERSITE DE RENNES ,  INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE RENNES

发明人： Maxime DUFOND ,  Jean Manuel DECAMS ,  Lionel SANTINACCI ,  Gabriel LOGET

IPC分类号： C25B11/089 ,  C25B11/059 ,  C25B11/087 ,  C23C16/40 ,  C23C16/455

CPC分类号： C25B11/089 ,  C25B11/059 ,  C25B11/087 ,  C23C16/405 ,  C23C16/406 ,  C23C16/45555

摘要： The invention relates to the use of a ternary alloy having the formula SixTiyNiz, wherein x, y and z are natural numbers, for use in electrolysis and photoelectrolysis, in particular photo-oxidation of water. One aspect of the invention relates to a method for the manufacture of an electrode, the method comprising a step of heating a carrier comprising a surface having a layer of silicon on which a layer of TiO2 is disposed, the layer of TiO2 being covered with a layer of NiO; the heating step being carried out at a temperature above 1,000° C., and preferably between 1,150° C. and 1,250° C. The invention also relates to an electrode comprising a carrier, said electrode having either: an outer surface on which particles of a ternary alloy having the formula SixTiyNiz are positioned, wherein x, y and z are natural numbers, and wherein the particles form protrusions; or an outer surface consisting of a layer of said alloy, the layer comprising protrusions.

公开(公告)号：US20230398527A1

公开(公告)日：2023-12-14

申请号：US18249135

申请日：2021-10-12

申请人： UNIVERSITE DE RENNES ,  Centre National de la Recherche Scientifique ,  École Nationale Supérieure de Chimie ,  Institut National des Sciences Appliquées de Rennes

发明人： Jean-François SOULÉ

IPC分类号： B01J31/02 ,  B01J35/00 ,  B01J37/34 ,  C07D219/02

CPC分类号： B01J31/0284 ,  B01J31/0298 ,  B01J35/004 ,  B01J37/344 ,  C07D219/02 ,  B01J2531/002 ,  B01J2231/005

摘要： The present invention belongs to the field of catalytic chemistry, and more specifically to catalysed oxidation of lignin. It also relates to synthesis of catalyst compounds.
The present invention relates to new acridinium-based photoredox catalyst compounds and their use thereof in a chemical reaction, preferably in depolymerisation of lignin models and ultimately lignin. The invention also relates to the method of synthesis of the new acridinium-based photoredox catalyst compounds according to the invention.

公开(公告)号：US11834429B2

公开(公告)日：2023-12-05

申请号：US17058197

申请日：2019-05-29

申请人： BOSTIK SA ,  CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE ,  UNIVERSITE DE RENNES 1

发明人： Guillaume Michaud ,  Stéphane Fouquay ,  Frédéric Simon ,  Cyril Chauveau ,  Sophie Guillaume ,  Jean-François Carpentier

IPC分类号： C07D317/40 ,  C08F212/08 ,  C08F220/14 ,  C08F220/28 ,  C08F220/18

CPC分类号： C07D317/40 ,  C08F212/08 ,  C08F220/14 ,  C08F220/283 ,  C08F220/1804 ,  C08F220/1811 ,  C08F220/40 ,  C08F212/08 ,  C08F220/1804 ,  C08F220/1811 ,  C08F220/14 ,  C08F212/08 ,  C08F220/1811 ,  C08F220/1804 ,  C08F220/14

摘要： The invention relates to a monoethylenically unsaturated monomer of formula (I), and to the use thereof for producing a polymer. The invention also relates to the polymer obtained by polymerising said monomer, and to the use thereof in a composition for producing coatings.

公开(公告)号：US20220315517A1

公开(公告)日：2022-10-06

申请号：US17642248

申请日：2020-09-14

申请人： DEMETA ,  UNIVERSITE DE RENNES 1

发明人： CORENTIN BORDIER ,  VINCENT ESCANDE ,  CHRISTOPHE DARCEL ,  FRÉDÉRIC CAIJO

IPC分类号： C07C51/25 ,  B01J31/02

摘要： The present invention relates to a method for oxidative cleavage of a substrate consisting of at least one functionalised or non-functionalised linear olefin, in particular a mono- or polyunsaturated aliphatic carboxylic acid, or one of the esters thereof, or at least one non-functionalised cyclic olefin, using hydrogen peroxide, in the presence of a metal catalyst which consists of at least one onium halooxodiperoxometallate. It also relates to a novel catalyst consisting of a specific onium halooxodiperoxometallate which can be used, in particular, in said method.

公开(公告)号：US11345184B2

公开(公告)日：2022-05-31

申请号：US16480465

申请日：2018-01-26

申请人： CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE—CNRS − ,  UNIVERSITE DE RENNES 1

发明人： Maxime Harnois ,  Jacques Emmanuel ,  Brice Le Borgne

IPC分类号： B44C1/175 ,  B41F7/02

摘要： A solvent transfer printing method for applying a pattern made of a non-soluble material and non-dispersible on the surface of an object. The method includes the steps of: m1/forming a pattern on a surface of a solvent-soluble substrate, m2/depositing the solvent-soluble substrate on the surface of a solvent bath, on the side of the substrate opposed to the side on which the pattern is applied, in order to dissolve partially the substrate, m3/dipping the object in the bath, so that the surface of the object comes into contact with the pattern, m4/getting the object, on which the pattern is applied, out of the bath, and b 5/drying the object.

公开(公告)号：US11171250B2

公开(公告)日：2021-11-09

申请号：US16305579

申请日：2017-05-22

申请人： SAFRAN ELECTRONICS & DEFENSE ,  CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE-CNRS- ,  UNIVERSITE DE RENNES 1

发明人： Cyril Dupeyrat ,  Patrice Foutrel ,  Philippe Besnier ,  Xavier Castel ,  Yonathan Corredores

IPC分类号： H01L31/00 ,  H01L31/0216 ,  H01L31/0203 ,  H01L31/18

摘要： A shielding element comprises a rigid substrate and at least one electrically conductive two-dimensional structure which is placed on one of the faces of the substrate. The substrate and the electrically conductive two-dimensional structure are such that the shielding element has optical-transmission and shielding-efficiency values at least one of which varies between two zones of the shielding element. Such a shielding element enables easier assembly of a detection system comprising multiple optical sensors.