- 专利标题: PH20 polypeptide variants, formulations and uses thereof
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申请号: US18068418申请日: 2022-12-19
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公开(公告)号: US12110520B2公开(公告)日: 2024-10-08
- 发明人: Ge Wei , H. Michael Shepard , Qiping Zhao , Robert James Connor
- 申请人: HALOZYME, INC.
- 申请人地址: US CA San Diego
- 专利权人: Halozyme, Inc.
- 当前专利权人: Halozyme, Inc.
- 当前专利权人地址: US CA San Diego
- 代理机构: Morgan, Lewis & Bockius LLP
- 分案原申请号: US17327568 2021.05.21
- 主分类号: C12N9/26
- IPC分类号: C12N9/26 ; A61K9/00 ; A61K38/00 ; A61K38/28 ; A61K38/47 ; A61K45/06 ; A61K47/10 ; A61P35/00 ; C07K14/47 ; C12Q1/34
摘要:
Modified PH20 hyaluronidase polypeptides, including modified polypeptides that exhibit increased stability and/or increased activity, are provided. Also provided are compositions and formulations and uses thereof.
公开/授权文献
- US20230250409A1 PH20 POLYPEPTIDE VARIANTS, FORMULATIONS AND USES THEREOF 公开/授权日:2023-08-10
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