Invention Grant
- Patent Title: Stable compositions of MRNA-loaded lipid nanoparticles and processes of making
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Application No.: US16936909Application Date: 2020-07-23
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Publication No.: US12144871B2Publication Date: 2024-11-19
- Inventor: Shrirang Karve , Frank DeRosa , Michael Heartlein , Natalia Vargas Montoya , Priyal Patel , Ashish Sarode
- Applicant: Translate Bio, Inc.
- Applicant Address: US MA Lexington
- Assignee: Translate Bio, Inc.
- Current Assignee: Translate Bio, Inc.
- Current Assignee Address: US MA Lexington
- Agency: MH2 Technology Law Group, LLP
- Main IPC: A61K48/00
- IPC: A61K48/00 ; A61K9/107 ; A61K47/32 ; A61K47/34
Abstract:
The present invention provides an improved compositions and processes for preparing mRNA-loaded lipid nanoparticles (mRNA-LNPs). In some embodiments, the present invention provides mRNA-LNPs with exceptional stability and is particularly useful in cases where LNPs comprising low or no PEG-modified lipids are desired.
Public/Granted literature
- US20210046192A1 STABLE COMPOSITIONS OF MRNA-LOADED LIPID NANOPARTICLES AND PROCESSES OF MAKING Public/Granted day:2021-02-18
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