Methods and apparatuses are described herein for multi-subscriber identification module (SIM) connected mode operation. In one embodiment, a wireless communications device may receive, from an access stratum interface, a request access to the receiver chain during a receiving opportunity. The wireless communications device may determine that the receiver chain is available during the receiving opportunity. The wireless communications device may send a response indicating access is granted to cause the access stratum interface to receive a downlink transmission during the receiving opportunity. The wireless communications device may receive, from the access stratum interface, a second request for a transmitter chain during a transmitting opportunity. The wireless communications device may determine that the transmitter chain is available during the transmitting opportunity. The wireless communications device may send a second response indicating access is granted to enable the access stratum interface to transmit an uplink transmission during the transmitting opportunity.