Invention Application
- Patent Title: Indane or dihydroindole derivatives
- Patent Title (中): 茚满或二氢吲哚衍生物
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Application No.: US09915680Application Date: 2001-07-26
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Publication No.: US20010051625A1Publication Date: 2001-12-13
- Inventor: Jens Kristian Perregaard , Ivan Mikkelsen , Henrik Pedersen
- Applicant: H. Lundbeck A/S
- Applicant Address: DK Copenhagen
- Assignee: H. Lundbeck A/S
- Current Assignee: H. Lundbeck A/S
- Current Assignee Address: DK Copenhagen
- Priority: DK1469/96 19961220; DKPCT/DK97/00588 19971219
- Main IPC: A61K031/496
- IPC: A61K031/496 ; C07D413/14 ; A61K031/454
Abstract:
The present invention relates to substituted indane or dihydroindole compounds of 1 Formula (I), wherein A and B are independently O or S; D is an optionally substituted methylene group; X is N or optionally substituted C; and W is a spacer group. The compounds are either selective dopamine D4 ligands or they have combined effects at dopamine D4 and serotonergic receptors and/or the serotonergic transporter. These compounds are therefore useful in the treatment of certain psychiatric and neurologic disorders, including psychosis, depression and anxiety.
Public/Granted literature
- US06436940B1 Indane or dihydroindole derivatives Public/Granted day:2002-08-20
Information query
