发明申请
- 专利标题: Bone morphogenetic protein-16 (BMP-16) compositions
- 专利标题(中): 骨形态发生蛋白-16(BMP-16)组合物
-
申请号: US09994177申请日: 2001-11-26
-
公开(公告)号: US20030158379A1公开(公告)日: 2003-08-21
- 发明人: Anthony J. Celeste , Beth L. Murray
- 申请人: Genetics Institute, Inc.
- 申请人地址: null
- 专利权人: Genetics Institute, Inc.
- 当前专利权人: Genetics Institute, Inc.
- 当前专利权人地址: null
- 主分类号: C07K014/51
- IPC分类号: C07K014/51
摘要:
Purified BMP-16 proteins and processes for producing them are disclosed. DNA molecules encoding the BMP-16 proteins are also disclosed. The proteins may be used in the treatment of bone, cartilage, other connective tissue defects and disorders, including tendon, ligament and meniscus, in wound healing and related tissue repair, as well as for treatment of disorders and defects to tissues which include epidermis, nerve, muscle, including cardiac muscle, and other tissues and wounds, and organs such as liver, lung, cardiac, pancreas and kidney tissue. The proteins may also be useful for the induction of growth and/or differentiation of undifferentiated embryonic and stem cells.
公开/授权文献
- US06623934B2 Bone morphogenetic protein-16 (BMP-16)antibodies 公开/授权日:2003-09-23