发明申请
US20040047806A1 Unsymmetrical methine and polymethine dye-molecules for fluorescent intracellular applications
失效
用于荧光细胞内应用的不对称次甲基和聚甲炔染料分子
- 专利标题： Unsymmetrical methine and polymethine dye-molecules for fluorescent intracellular applications
- 专利标题（中）： 用于荧光细胞内应用的不对称次甲基和聚甲炔染料分子
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申请号： US10658091申请日： 2003-09-09
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公开(公告)号： US20040047806A1公开(公告)日： 2004-03-11
- 发明人: Spyros Theodoropulos
- 主分类号： G01N001/30
- IPC分类号： G01N001/30 ; G01N033/48 ; C07D417/02 ; C07D43/02 ; C07D413/02 ; C07D213/57
摘要：
A new class of alpha-cyanomethine and alpha-cyanopolymethine dyes is provided having moieties which serve for the covalent attachment to biological substrates and resulting in the fluorescent labeling of the substrates. The labeled substrates are useful in analytical techniques for the detection and measurement of biological and clinical compounds of interest. Of particular interest is a class of methine molecules which are non-fluorescent in buffer solutions but intensely fluoresce when they enter a cell.
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