发明申请
US20040053921A1 Compounds useful as reversible inhibitors of cysteine proteases
有权
可用作半胱氨酸蛋白酶的可逆抑制剂的化合物
- 专利标题: Compounds useful as reversible inhibitors of cysteine proteases
- 专利标题(中): 可用作半胱氨酸蛋白酶的可逆抑制剂的化合物
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申请号: US10279424申请日: 2002-10-24
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公开(公告)号: US20040053921A1公开(公告)日: 2004-03-18
- 发明人: Younes Bekkali , Denice Mary Spero , Sanxing Sun , Yancey David Ward
- 申请人: Boehringer Ingelheim Pharmaceuticals, Inc.
- 申请人地址: CT Ridgefield
- 专利权人: Boehringer Ingelheim Pharmaceuticals, Inc.
- 当前专利权人: Boehringer Ingelheim Pharmaceuticals, Inc.
- 当前专利权人地址: CT Ridgefield
- 主分类号: A61K031/541
- IPC分类号: A61K031/541 ; A61K031/5383 ; A61K031/538 ; A61K031/5377 ; A61K031/52 ; A61K031/517 ; C07D491/02 ; C07D473/00 ; C07D417/02 ; C07D45/02
摘要:
Disclosed are cathepsin S, K, F, L and B reversible inhibitory compounds of the formulas (Ia) and (Ib) where R2, R3, R4, R6, R8 and Y are defined herein. The compounds are useful for treating autoimmune and other diseases. Also disclosed are processes for making such novel compounds. 1
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