发明申请
- 专利标题: Pyrazole-amide compounds useful as kinase inhibitors
- 专利标题(中): 用作激酶抑制剂的吡唑酰胺化合物
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申请号: US10837778申请日: 2004-05-03
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公开(公告)号: US20050004176A1公开(公告)日: 2005-01-06
- 发明人: Alaric Dyckman , Jagabandhu Das , Katerina Leftheris , Chunjian Liu , Robert Moquin , Stephen Wrobleski
- 申请人: Alaric Dyckman , Jagabandhu Das , Katerina Leftheris , Chunjian Liu , Robert Moquin , Stephen Wrobleski
- 主分类号: A61K
- IPC分类号: A61K20060101 ; A61K31/415 ; A61K31/4152 ; A61K31/4155 ; A61K31/416 ; A61K31/4439 ; A61K31/497 ; A61K31/501 ; A61K31/506 ; A61K31/535 ; A61K31/675 ; C07D20060101 ; C07D231/04 ; C07D231/14 ; C07D231/18 ; C07D401/04 ; C07D401/12 ; C07D403/04 ; C07D405/12 ; C07D413/12 ; C07D413/14 ; C07
摘要:
The present invention provides pyrazole derived compounds of formula (I) useful for treating p38 kinase-associated conditions, where G, X, R1, R2, R3, R4, R5, R6 and m are as defined herein. The invention further pertains to pharmaceutical compositions containing at least one compound according to the invention useful for treating p38 kinase-associated conditions, and methods of inhibiting the activity of p38 kinase in a mammal.
公开/授权文献
- US07414056B2 Pyrazole-amide compounds useful as kinase inhibitors 公开/授权日:2008-08-19
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