Invention Application
US20050014722A1 Process for preparing n-acylated lysophosphatidylcholine and pharmaceutical composition for treatment of metabolic bone disease comprising said compounds
审中-公开
制备正酰化溶血磷脂酰胆碱的方法和用于治疗包含所述化合物的代谢性骨病的药物组合物
- Patent Title: Process for preparing n-acylated lysophosphatidylcholine and pharmaceutical composition for treatment of metabolic bone disease comprising said compounds
- Patent Title (中): 制备正酰化溶血磷脂酰胆碱的方法和用于治疗包含所述化合物的代谢性骨病的药物组合物
-
Application No.: US10497893Application Date: 2002-12-13
-
Publication No.: US20050014722A1Publication Date: 2005-01-20
- Inventor: Gil-Ja Jhon , So-Yeon Han , Zang-Hee Lee , Hong-Hee Kim , Eun-Hee Lee , Young-Ah Kim , Han-Bok Kwak
- Applicant: Gil-Ja Jhon , So-Yeon Han , Zang-Hee Lee , Hong-Hee Kim , Eun-Hee Lee , Young-Ah Kim , Han-Bok Kwak
- Priority: KR2001/79100 20011213
- International Application: PCT/KR02/02357 WO 20021213
- Main IPC: A61K31/661
- IPC: A61K31/661 ; A61K31/14 ; A61K31/16 ; A61K31/6615 ; C07F9/09 ; C07F9/10 ; A61K31/685
Abstract:
Disclosed is a pharmaceutical composition for treating and preventing metabolic bone diseases, comprising a pharmaceutically effective amount of N-acylated lysophosphatidylcholine compound represented by Formula 1 (R is a saturated or unsaturated fatty acid of C14 to C20, and R′ is methoxycarbonyl or hydroxylmethyl group), and a pharmaceutically acceptable carrier. Also, the present invention discloses a method of preparing an N-acylated lysophosphatidylcholine compound represented by Formula 1, from serine. [Formula 1]
Information query
