Invention Application
- Patent Title: MHC-antigen arrays for detection and characterization of immune responses
- Patent Title (中): MHC抗原阵列用于检测和表征免疫应答
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Application No.: US10856185Application Date: 2004-05-27
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Publication No.: US20050019843A1Publication Date: 2005-01-27
- Inventor: Daniel Chen , Yoav Soen , Daniel Kraft , Patrick Brown , Mark Davis
- Applicant: Daniel Chen , Yoav Soen , Daniel Kraft , Patrick Brown , Mark Davis
- Assignee: The Board of Trustees of the Leland Stanford Junior University
- Current Assignee: The Board of Trustees of the Leland Stanford Junior University
- Main IPC: C40B30/04
- IPC: C40B30/04 ; G01N33/569 ; G01N33/68 ; A61K45/00 ; G01N33/567
Abstract:
T cells are profiled with respect to their expression of antigen receptor. The cells are arrayed on a planar or three-dimensional substrate through binding to immobilized or partially diffused MHC-antigen complexes. The cells may further be characterized with respect to their ability to respond to external stimulus in the microenvironment. External stimuli include cell-cell interactions, response to factors, and the like.
Public/Granted literature
- US07902121B2 MHC-antigen arrays for detection and characterization of immune responses Public/Granted day:2011-03-08
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