Invention Application
US20050020576A1 Kappa agonist compounds and pharmaceutical formulations thereof
审中-公开
卡帕激动剂化合物及其药物制剂
- Patent Title: Kappa agonist compounds and pharmaceutical formulations thereof
- Patent Title (中): 卡帕激动剂化合物及其药物制剂
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Application No.: US10807113Application Date: 2004-03-23
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Publication No.: US20050020576A1Publication Date: 2005-01-27
- Inventor: Wei Zhang , Alan Maycock , Michael Marella , Virendra Kumar , Forrest Gaul , Michael Chang , Deqi Guo
- Applicant: Wei Zhang , Alan Maycock , Michael Marella , Virendra Kumar , Forrest Gaul , Michael Chang , Deqi Guo
- Assignee: Adolor Corporation
- Current Assignee: Adolor Corporation
- Main IPC: A61K31/404
- IPC: A61K31/404 ; A61K31/4439 ; A61K45/06 ; C07D207/12 ; C07D209/42 ; C07D213/56 ; C07D241/04 ; C07D295/073 ; C07D403/06 ; A61K31/55 ; A61K31/40 ; A61K31/445
Abstract:
Compounds having kappa opioid agonist activity, compositions containing them and method of using them as analgesics are provided. The compounds of formulae I, II, IIA, III, IIIA, IIIB, IIB-i, IV and IVA have the structure: wherein R1, R2, R3, R4; and X, X4, X5, X7, X9; Y, Z and n are as described in the specification.
Information query
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