发明申请
- 专利标题： Methods and pharmaceutical compositions for reliable achievement of acceptable serum testosterone levels
- 专利标题（中）： 可靠地达到可接受的血清睾酮水平的方法和药物组合物
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申请号： US10798780申请日： 2004-03-12
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公开(公告)号： US20050032762A1公开(公告)日： 2005-02-10
- 发明人: Doris Hubler , Sabine Fricke , Jan-Peter Ingwersen , Wilhelm Kuhnz
- 申请人： Doris Hubler , Sabine Fricke , Jan-Peter Ingwersen , Wilhelm Kuhnz
- 主分类号： A61K9/00
- IPC分类号： A61K9/00 ; A61K31/56 ; A61K31/565 ; A61K31/568 ; A61K31/57 ; A61K36/47 ; A61K47/14 ; A61K47/44 ; A61K35/78
摘要：
The present invention relates to pharmaceutical compositions, formulated for injectable administration, which comprises a testosterone ester, in particularly testosterone undecanoate, in a vehicle comprising castor oil and a co-solvent. Upon injecting the compositions according to a particular administration scheme, reliable levels of testosterone in serum in the normal physiological range is achieved for a long period. This allows for the use of the compositions in hormone replacement therapy and male contraception without concomitant monitoring of testosterone levels in serum by a physician.
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