发明申请
- 专利标题： Piperazine derivatives
- 专利标题（中）： 哌嗪衍生物
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申请号： US10910984申请日： 2004-08-03
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公开(公告)号： US20050043300A1公开(公告)日： 2005-02-24
- 发明人: Donald Middleton , Charles Mowbray , Peter Stephenson , David Williams
- 申请人： Donald Middleton , Charles Mowbray , Peter Stephenson , David Williams
- 专利权人： PFIZER INC.
- 当前专利权人： PFIZER INC.
- 优先权： GB0319149.1 20030814; GB0322153.8 20030922; GB0406656.9 20040324
- 主分类号： C07D213/64
- IPC分类号： C07D213/64 ; C07D213/81 ; C07D215/20 ; C07D215/22 ; C07D215/227 ; C07D215/26 ; C07D215/38 ; C07D215/48 ; C07D217/02 ; C07D217/22 ; C07D217/24 ; C07D217/26 ; C07D231/12 ; C07D231/56 ; C07D233/54 ; C07D235/08 ; C07D239/74 ; C07D249/08 ; C07D263/56 ; C07D271/06 ; C07D295/192 ; C07D401/04 ; C07D401/12 ; A61K31/541 ; A61K31/496 ; A61K31/517 ; A61K31/5377 ; C07D413/02 ; C07D417/02 ; C07D43/02
摘要：
This invention relates to a compound of formula (I) or pharmaceutically acceptable salts, solvates or derivatives thereof, wherein R1 to R5 are defined in the description, and to processes for the preparation thereof, intermediates used in their preparation, compositions containing them and the uses of such derivatives. The compounds of the present invention inhibit the interaction of gp120 with CD4 and are therefore of use in the treatment of HIV, a retroviral infection genetically related to HIV, or AIDS.
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