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发明申请
US20050053659A1 Methods and compositions for reducing the risk associated with the administration of opioid analgesics in patients with diagnosed or undiagnosed respiratory illness 审中-公开
用于降低诊断或未诊断呼吸系统疾病患者阿片样镇痛药相关风险的方法和组合物

  • 专利标题： Methods and compositions for reducing the risk associated with the administration of opioid analgesics in patients with diagnosed or undiagnosed respiratory illness
  • 专利标题（中）： 用于降低诊断或未诊断呼吸系统疾病患者阿片样镇痛药相关风险的方法和组合物
  • 申请号： US10661458
    申请日： 2003-09-10
  • 公开(公告)号： US20050053659A1
    公开(公告)日： 2005-03-10
  • 发明人: Gary Pace , Maree Smith
  • 申请人： Gary Pace , Maree Smith
  • 主分类号： A61K9/22
  • IPC分类号： A61K9/22 ;  A61K31/445 ;  A61K31/485 ;  A61K45/06 ;  A61P11/00 ;  A61P25/04
Methods and compositions for reducing the risk associated with the administration of opioid analgesics in patients with diagnosed or undiagnosed respiratory illness
摘要：
The present invention relates to methods for reducing the risk associated with the administration of opioid analgesics in patients diagnosed or undiagnosed with respiratory illness by administering an analgesic composition comprising a sub-analgesic dosage of a μ-opioid agonist selected from the group consisting of morphine, fentanyl, sufentanil, alfentanil, oxymorphone and hydromorphone, or a pharmaceutically acceptable salt thereof, and a sub-analgesic dosage of oxycodone which is a κ2-opioid agonist or a pharmaceutically acceptable salt thereof.
摘要（中）：

本发明涉及通过施用镇痛组合物来降低与诊断或未诊断呼吸系统疾病的患者中阿片样镇痛药相关的风险的方法，所述镇痛组合物包含选自以下的阿片样物质激动剂：吗啡， 芬太尼，舒芬太尼，阿芬太尼，羟吗啡酮和氢吗啡酮，或其药学上可接受的盐，以及作为κ-阿片样物质激动剂或其药学上可接受的盐的羟考酮的次镇痛剂量。

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