发明申请
- 专利标题: Use of polysaccharide derivatives as anti-infective substances
- 专利标题(中): 多糖衍生物作为抗感染物质的使用
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申请号: US10500807申请日: 2003-01-10
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公开(公告)号: US20050054609A1公开(公告)日: 2005-03-10
- 发明人: Vera Haack , Thomas Heinze , Michaela Schmidtke , Ute Mollmann , Hans-Martin Dahse , Albert Hartl
- 申请人: Vera Haack , Thomas Heinze , Michaela Schmidtke , Ute Mollmann , Hans-Martin Dahse , Albert Hartl
- 优先权: DE10200717.9 20020110
- 国际申请: PCT/DE03/00095 WO 20030110
- 主分类号: A61K8/72
- IPC分类号: A61K8/72 ; A01N33/12 ; A01N63/00 ; A61K8/73 ; A61K31/715 ; A61K31/716 ; A61K31/717 ; A61K31/718 ; A61K31/719 ; A61K31/721 ; A61P31/04 ; A61P31/12 ; C08B31/12
摘要:
The present invention relates to a method of treating infectious diseases, that involves: (a) providing an alpha-glycosidically linked starch polysaccharide derivative; and (b) inhibiting the growth of an infectious disease by administering a composition comprising the alpha-glycosidically linked starch polysaccharide derivative. The alpha-glycosidically linked starch polysaccharide derivative represented by the following general formula I, in which: the alpha-glycosidically linked starch polysaccharide derivative has a degree of quaternary ammonium group substitution of from 0.4 to 2.0; n is 2-4; R1 is selected from the group consisting of C1-4 alkyl, benzyl and benzyl substituted with a member selected from the group consisting of C1-3 alkyl, halogen, alcoxy, carbamoyl, alkoxycarbonyl, cyano, dialkylamino and hydrogen; R2 and R3 are each independently selected from the group consisting of C1-4 alkyl, benzyl and benzyl substituted with a member selected from the group consisting of C1-3 alkyl, halogen, alcoxy, carbamoyl, alkoxycarbonyl, cyano and dialkylamino; and X is an anion selected from the group consisting of halide, hydroxide, sulfate, hydrogen sulfate and carboxylate.
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