发明申请
US20050054638A1 Pyrimidine derivatives as modulators of insulin-like growth factor-1 receptor (igf-i)
失效
嘧啶衍生物作为胰岛素样生长因子-1受体(igf-i)的调节剂
- 专利标题: Pyrimidine derivatives as modulators of insulin-like growth factor-1 receptor (igf-i)
- 专利标题(中): 嘧啶衍生物作为胰岛素样生长因子-1受体(igf-i)的调节剂
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申请号: US10497744申请日: 2002-12-03
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公开(公告)号: US20050054638A1公开(公告)日: 2005-03-10
- 发明人: Bernard Barlaam , Andrew Pape , Andrew Thomas
- 申请人: Bernard Barlaam , Andrew Pape , Andrew Thomas
- 专利权人: AstraZeneca AB
- 当前专利权人: AstraZeneca AB
- 优先权: SE0104140-9 20011207
- 国际申请: PCT/SE02/02221 WO 20021203
- 主分类号: A61K31/505
- IPC分类号: A61K31/505 ; A61K31/506 ; A61P35/00 ; A61P43/00 ; C07D239/48 ; C07D401/14 ; C07D403/12 ; C07D403/14 ; C07D405/14 ; C07D409/14 ; C07D413/14 ; A61K31/541 ; A61K31/5377 ; C07D413/04 ; C07D417/04 ; C07D43/04
摘要:
The invention provides compounds of formula in which R1, R2, R3 and R4 have the meanings defined in the specification; processes for the preparation; pharmaceutical compositions containing them; a process for preparing the pharmaceutical compositions; and their use in therapy.