发明申请
US20050054643A1 Substituted polycyclic aryl and heteroaryl pyrimidinones useful for selective inhibition of the coagulation cascade
审中-公开
用于选择性抑制凝血级联的取代的多环芳基和杂芳基嘧啶酮
- 专利标题： Substituted polycyclic aryl and heteroaryl pyrimidinones useful for selective inhibition of the coagulation cascade
- 专利标题（中）： 用于选择性抑制凝血级联的取代的多环芳基和杂芳基嘧啶酮
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申请号： US10680873申请日： 2003-10-07
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公开(公告)号： US20050054643A1公开(公告)日： 2005-03-10
- 发明人: Michael South , Ashton Hamme , William Neumann , Darin Jones , Melvin Rueppel
- 申请人： Michael South , Ashton Hamme , William Neumann , Darin Jones , Melvin Rueppel
- 专利权人： Pharmacia Corporation
- 当前专利权人： Pharmacia Corporation
- 主分类号： C07D239/46
- IPC分类号： C07D239/46 ; C07D239/47 ; C07D253/07 ; C07D401/04 ; C07D417/12 ; A61K31/53
摘要：
The invention relates to substituted polycyclic aryl and heteroaryl pyrimidinone compounds useful as inhibitors of serine proteases of the coagulation cascade and compounds, compositions and methods for anticoagulant therapy for the treatment and prevention of a variety of thrombotic conditions including coronary artery and cerebrovascular diseases.
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