发明申请
US20050059612A1 Bicyclic carbohydrates as antiviral bioactives for the treatment of infections caused by the alphaherpesvirinae HSV-1 and HSV-2
失效
双环碳水化合物作为抗病毒生物活性物质，用于治疗由αherpesvirinaeHSV-1和HSV-2引起的感染
- 专利标题： Bicyclic carbohydrates as antiviral bioactives for the treatment of infections caused by the alphaherpesvirinae HSV-1 and HSV-2
- 专利标题（中）： 双环碳水化合物作为抗病毒生物活性物质，用于治疗由αherpesvirinaeHSV-1和HSV-2引起的感染
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申请号： US10663962申请日： 2003-09-16
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公开(公告)号： US20050059612A1公开(公告)日： 2005-03-17
- 发明人: Benedikt Sas , Johan hemel , Jan Vandenkerckhove , Eric Peys , Johan Eycken , Steven Hoof
- 申请人： Benedikt Sas , Johan hemel , Jan Vandenkerckhove , Eric Peys , Johan Eycken , Steven Hoof
- 主分类号： C07D493/02
- IPC分类号： C07D493/02 ; C07H15/04 ; A61K31/70
摘要：
Novel bicyclic carbohydrate compounds are effective for the prophylaxis and treatment of diseases caused by infections of the alphaherpesvirinae HSV-1 and HSV-2. The invention includes the compound wherein X1, X2, and X3 are selected from the group consisting of O, N, and S; wherein Y1 and Y2 are selected from the group consisting of O, N, and S; and wherein Z is selected from the group consisting of F, Cl, and Br, as well as analogs, prodrugs and pharmaceutically acceptable salts thereof, together with pharmaceutical compositions for the prophylaxis and treatment of diseases caused by infections of alphaherpesvirinae.