发明申请
US20050074791A1 L-lysine-producing corynebacteria and process for the preparation of L-lysine
有权
L-赖氨酸生产棒杆菌和制备L-赖氨酸的方法
- 专利标题： L-lysine-producing corynebacteria and process for the preparation of L-lysine
- 专利标题（中）： L-赖氨酸生产棒杆菌和制备L-赖氨酸的方法
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申请号： US10804120申请日： 2004-03-19
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公开(公告)号： US20050074791A1公开(公告)日： 2005-04-07
- 发明人: Caroline Kreutzer , Stephan Hans , Mechthild Rieping , Bettina Mockel , Walter Pfefferle , Lothar Eggeling , Hermann Sahm , Miroslav Patek
- 申请人： Caroline Kreutzer , Stephan Hans , Mechthild Rieping , Bettina Mockel , Walter Pfefferle , Lothar Eggeling , Hermann Sahm , Miroslav Patek
- 申请人地址： DE Frankfurt am Main DE-60311 DE Julich D-52425
- 专利权人： Degussa-Huls Aktiengesellachaft,Forschungszentrum Julich GmbH
- 当前专利权人： Degussa-Huls Aktiengesellachaft,Forschungszentrum Julich GmbH
- 当前专利权人地址： DE Frankfurt am Main DE-60311 DE Julich D-52425
- 优先权： DE19931317.2 19990707
- 主分类号： C07K14/34
- IPC分类号： C07K14/34 ; C12N1/21 ; C12N15/52 ; C12P13/08 ; C12Q1/68
摘要：
The invention relates to L-lysine-producing strains of corynebacteria with enhanced lysE gene (lysine export carrier gene), in which strains additional genes chosen from the group comprising the dapA gene (dihydrodipicolinate synthase gene), the lysC gene (aspartate kinase gene), the dapB gene (dihydrodipicolinate reductase gene) and the pyc gene, but especially the dapA gene and the lysC gene (aspartate kinase gene), are enhanced and, in particular, over-expressed, and to a process for the preparation of L-lysine.
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