Invention Application
US20050089471A1 Labeled ligands for lectin-like oxidized low-density lipoprotein receptor (LOX-1)
审中-公开
凝集素样氧化低密度脂蛋白受体（LOX-1）的标记配体
- Patent Title: Labeled ligands for lectin-like oxidized low-density lipoprotein receptor (LOX-1)
- Patent Title (中): 凝集素样氧化低密度脂蛋白受体（LOX-1）的标记配体
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Application No.: US10691533Application Date: 2003-10-24
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Publication No.: US20050089471A1Publication Date: 2005-04-28
- Inventor: Bruce Johnson , Frank Mondello , Faisal Syud , Andrew Torres , John Brogan
- Applicant: Bruce Johnson , Frank Mondello , Faisal Syud , Andrew Torres , John Brogan
- Main IPC: A61K49/00
- IPC: A61K49/00 ; A61K49/14 ; A61K49/16 ; A61K51/10 ; C07B59/00 ; A61K51/00 ; C07F5/00 ; C07F13/00
Abstract:
Embodiments of the present invention relates to compounds labeled with imaging agents that also are capable of binding lectin-like oxidized low-density lipoprotein (LOX-1). The labeled compounds are useful for the diagnosis and monitoring of diseases in which inflammation plays a role, such as various cardiovascular diseases including but not limited to atherosclerosis, vulnerable plaque, and coronary artery disease, as well as rheumatoid arthritis.
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